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1

New contributions to the study of common double mutants in the humanLDLreceptor gene

M. Teresa Tejedor, Ana Cenarro, Diego Tejedor, Marianne Stef, Lourdes Palacios, Isabel de Castro, Ángel L. García-Otín, Luis V. Monteagudo, Fernando Civeira, Miguel Pocovi

Journal:

Naturwissenschaften (The Science of Nature)

Year:

2011

Language:

english

File:

PDF, 131 KB

english, 2011

2

ImageJ-based semiautomatic method to analyze senescence in cell culture

Lozano-Gerona, Javier, García-Otín, Ángel-Luis

Journal:

Analytical Biochemistry

Year:

2017

Language:

english

File:

PDF, 543 KB

english, 2017

3

A novel DNA polymorphism (4886C>T) in the human LCAT gene

Delia Recalde, Ana Cenarro, Fernando Civeira, Angel-Luis Garcia-Otin, Miguel Pocovi

Journal:

Year:

2000

Language:

english

File:

PDF, 14 KB

english, 2000

4

Allelic polymorphism −491A/T in apo E gene modulates the lipid-lowering response in combined hyperlipidemia treatment

A.-L. García-Otín, F. Civeira, R. Aristegui, C. Díaz, D. Recalde, J. M. Sol, X. Masramon, G. Hernández, M. Pocoví, the ATOMIX Study Group

Journal:

European Journal of Clinical Investigation

Year:

2002

Language:

english

File:

PDF, 125 KB

english, 2002

5

Role of naturally-occurring plant sterols on intestinal cholesterol absorption and plasmatic levels

T. Sanclemente, I. Marques-Lopes, J. Puzo, A. L. García-Otín

Journal:

Journal of Physiology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 157 KB

english, 2009

6

A moderate intake of phytosterols from habitual diet affects cholesterol metabolism

T. Sanclemente, I. Marques-Lopes, M. Fajó-Pascual, M. Cofán, E. Jarauta, E. Ros, J. Puzo, A. L. García-Otín

Journal:

Journal of Physiology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 97 KB

english, 2009

7

Haplotype analyses, mechanism and evolution of common double mutants in the humanLDLreceptor gene

M. T. Tejedor, A. Cenarro, D. Tejedor, M. Stef, R. Mateo-Gallego, I. de Castro, A. L. García-Otin, L. V. Monteagudo, F. Civeira, M. Pocovi

Journal:

Molecular Genetics and Genomics

Year:

2010

Language:

english

File:

PDF, 347 KB

english, 2010

8

Hyperlipoproteinaemia(a) is a common cause of autosomal dominant hypercholesterolaemia

E. Meriño-Ibarra, J. Puzo, E. Jarauta, A. Cenarro, D. Recalde, Á. L. García-Otín, E. Ros, E. Martorell, X. Pintó, M. Franco, D. Zambón, Á. Brea, M. Pocoví, F. Civeira

Journal:

Journal of Inherited Metabolic Disease

Year:

2007

Language:

english

File:

PDF, 308 KB

english, 2007

9

Atorvastatin Decreases Stearoyl-CoA Desaturase Gene Expression in THP-1 Macrophages Incubated with Oxidized LDL

Paula Martín-Fuentes, Angel Luis García-Otín, Luisa Calvo, Diego Gómez-Coronado, Fernando Civeira, Ana Cenarro

Journal:

Year:

2009

Language:

english

File:

PDF, 267 KB

english, 2009

10

A presumptive new locus for autosomal dominant hypercholesterolemia mapping to 8q24.22

A Cenarro, A-L García-Otín, MT Tejedor, M Solanas, E Jarauta, C Junquera, E Ros, P Mozas, J Puzo, M Pocoví, F Civeira

Journal:

Clinical Genetics

Year:

2011

Language:

english

File:

PDF, 623 KB

english, 2011

11

Síntesis y purificación de apolipoproteína apo A-I Zaragoza (L144R) recombinante

Sarah Fiddyment Puertas, Miguel Pocoví Mieras, Ángel-Luis García-Otín

Journal:

Clínica e Investigación en Arteriosclerosis

Year:

2010

File:

PDF, 324 KB

2010

12

Estudio genético de la implicación del gen USF1 en el desarrollo del síndrome metabólico

Mark Strunk, Estíbaliz Jarauta Simón, Ana María Bea Sanz, José Puzo Foncillas, Fernando Civeira Murillo, Ángel-Luis García-Otín

Journal:

Clínica e Investigación en Arteriosclerosis

Year:

2011

File:

PDF, 321 KB

2011

13

An NPC1L1 gene promoter variant is associated with autosomal dominant hypercholesterolemia

B. Martín, M. Solanas-Barca, Á.-L. García-Otín, S. Pampín, M. Cofán, E. Ros, J.-C. Rodríguez-Rey, M. Pocoví, F. Civeira

Journal:

Nutrition, Metabolism and Cardiovascular Diseases

Year:

2010

Language:

english

File:

PDF, 216 KB

english, 2010

14

Association of plasma markers of cholesterol homeostasis with metabolic syndrome components. A cross-sectional study

M. Cofán, V. Escurriol, A.L. García-Otín, C. Moreno-Iribas, N. Larrañaga, M.J. Sánchez, M.J. Tormo, M.L. Redondo, C.A. González, D. Corella, M. Pocoví, F. Civeira, E. Ros

Journal:

Nutrition, Metabolism and Cardiovascular Diseases

Year:

2011

Language:

english

File:

PDF, 168 KB

english, 2011

15

Expression and purification of recombinant apolipoprotein A-I Zaragoza (L144R) and formation of reconstituted HDL particles

Sarah Fiddyment, Sílvia Barceló-Batllori, Miguel Pocoví, Ángel-Luis García-Otín

Journal:

Protein Expression and Purification

Year:

2011

Language:

english

File:

PDF, 687 KB

english, 2011

16

Comparison of the hypolipidemic effect of gemfibrozil versus simvastatin in patients with type III hyperlipoproteinemia

Fernando Civeira, Ana Cenarro, Juan Ferrando, José Puzo, Angel L. Garcia-Otín, Pilar Mozas, Miguel Pocoví

Journal:

American Heart Journal

Year:

1999

Language:

english

File:

PDF, 148 KB

english, 1999

17

Plasma lipoprotein responses to enzyme-replacement in Gaucher's disease

Ana Cenarro, Miguel Pocovi, Pilar Giraldo, Angel L Garcia-Otin, Jose M Ordovas

Journal:

Year:

1999

Language:

english

File:

PDF, 352 KB

english, 1999

18

Sobreexpresión génica de citocinas proinflamatorias en macrófagos de sujetos con hipercolesterolemia familiar y xantomas tendinosos

Paula Martín-Fuentes, Fernando Civeira, María Solanas-Barca, Estíbaliz Jarauta, Ángel-Luis García-Otín, Pilar Calmarza, Ana Cenarro

Journal:

Clínica e Investigación en Arteriosclerosis

Year:

2008

File:

PDF, 103 KB

2008

19

Proteomic study of macrophages exposed to oxLDL identifies a CAPG polymorphism associated with carotid atherosclerosis

Elena Burillo, Delia Recalde, Estibaliz Jarauta, Sarah Fiddyment, Angel Luis Garcia-Otin, Rocio Mateo-Gallego, Ana Cenarro, Fernando Civeira

Journal:

Atherosclerosis

Year:

2009

Language:

english

File:

PDF, 339 KB

english, 2009

20

W14.349 Molecular analysis of hepatic lipase gene in subjects with combined hyperlipidemia

Cenarro, A., Artieda, M., García-Otín, A., Pocoví, M., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

21

Mo-P6:396 Novel DNA sequence variations in endothelial lipase gene in subjects with high HDL-cholesterol levels

Cenarro, A., Ghisoni, F., Martín-Fuentes, P., Recalde, D., García-Otín, A.L., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

22

Tu-P7:220 Inter-individual variability in the inflammatory response to oxidized LDL: Identification of high- and low-responders

Martin-Fuentes, P., Artieda, M., Recalde, D., Garcia-Otin, A.L., Cenarro, A., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 152 KB

english, 2006

23

GENETIC ANALYSIS OF NPC1L1 AND ABCG5/ABCG8 GENES IN AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA NOT RELATED TO LDLR OR APOB GENES

Garcia-Otin, A., Solanas, M., deCastro, I., Martin, B., Pocovi, M., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

24

MUTATIONS IN THE LDLR AND APOB IN SUBJECTS WITH THE CLINICAL DIAGNOSIS OF FAMILIAL COMBINED HYPERLIPERLIPIDEMIA

Civeira, F., Jarauta, E., Cenarro, A., Garcia-Otin, A.L., Ros, E., Tejedor, D., Pocovi, M.

Journal:

Atherosclerosis Supplements

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

25

Abstract: P462 THE CONTENT OF MARINE N-3 FATTY ACIDS IN SERUM PHOSPHATIDYLCHOLINE IS INVERSELY ASSOCIATED WITH SMALL AND VERY SMALL LDL PARTICLE CONCENTRATION INDEPENDENTLY OF TRIGLYCERIDES IN PATIENTS WITH A MOLECULAR DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA

Sala-Vila, A, Cofán, M, Junyent, M, Zambón, D, García-Otín, á, Cenarro, A, Civeira, F, Ros, E

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 87 KB

english, 2009

26

Abstract: P421 PRODUCTION OF RECOMBINANT APOLIPOPROTEIN A-I ZARAGOZA (L144R) FOR STRUCTURAL AND FUNCTIONAL CHARACTERIZATION

Fiddyment, S, Pocovi, M, Burillo, E, Solanas, M, Garcia-Otin, A-L

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

27

Novel antiangiogenic therapies against advanced hepatocellular carcinoma (HCC)

R. A. Pazo-Cid, M. Lanzuela, G. Esquerdo, J. L. Pérez-Gracia, A. Antón, G. Amigo, J. Martínez Trufero, A. L. García-Otín, P. Martín-Duque

Journal:

Clinical and Translational Oncology

Year:

2012

Language:

english

File:

PDF, 288 KB

english, 2012

28

Frequency of Low-Density Lipoprotein Receptor Gene Mutations in Patients With a Clinical Diagnosis of Familial Combined Hyperlipidemia in a Clinical Setting

Fernando Civeira, Estibaliz Jarauta, Ana Cenarro, Angel L. García-Otín, Diego Tejedor, Daniel Zambón, Miguel Mallen, Emilio Ros, Miguel Pocoví

Journal:

Journal of the American College of Cardiology

Year:

2008

Language:

english

File:

PDF, 258 KB

english, 2008

29

Naturally-occurring phytosterols in the usual diet influence cholesterol metabolism in healthy subjects

T. Sanclemente, I. Marques-Lopes, M. Fajó-Pascual, M. Cofán, E. Jarauta, E. Ros, J. Puzo, A.L. García-Otín

Journal:

Nutrition, Metabolism and Cardiovascular Diseases

Year:

2012

Language:

english

File:

PDF, 148 KB

english, 2012

30

−491 A/T polymorphism in the apo E gene promoter region modulates the lipid lowering response to atorvastatin and bezafibrate in patients with mixed dyslipidemia

A.L García-Otín, F Civeira, R Aristegui, X Masramon, C Díaz, G Hernández, M Pocoví

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 141 KB

english, 2000

31

Polymorphisms in apo E gene promoter. Frequency in Spanish newborns, elderly and coronary patients. Relationship with coronary stenosis levels

A. Gañán, A.L. García-Otín, J.M. Casado, C. Gonzalvo, J. Puzo, A. Cenarro, M. Pocoví, F. Civeira

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

32

Apo E variants in patients with type III hyperlipoproteinemia

Fernando Civeira, Miguel Pocoví, Ana Cenarro, Elena Casao, Elisabet Vilella, Jordi Joven, José González, Angel L. Garcia-Otín, JoséM. Ordovás

Journal:

Atherosclerosis

Year:

1996

Language:

english

File:

PDF, 1.43 MB

english, 1996

33

1.P.36 Frequency of lipoprotein lipase gene mutations in subjects with hypertriglyceridemia. Interaction with apo E genotype

A. García-Otín, A. Cenarro, P. Mozas, F. Civeira, J. González-Bonillo, M. Pocoví

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 183 KB

english, 1997

34

1.P.123 Hyperchylomicronemia syndrome due to low lipoprotein lipase activity associated with chronic idiopathic urticaria

F. Civeira, A. García-Otín, J. Peinado, M. Llovera, J. Ferrando, A. Cenarro, M. Pocoví

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 174 KB

english, 1997

35

Influence of apolipoprotein E polymorphism on the effect of atorvastatin and bezafibrate in patients with mixed dyslipidemia, atomix study

L. Garcia-Otin, R. Aristegui, C. Diaz, J.Ma. Sol, G. Hernández, M. Pocovi

Journal:

Atherosclerosis

Year:

1999

Language:

english

File:

PDF, 145 KB

english, 1999

36

Sensibilidad y especificidad de los criterios del síndrome metabólico para el diagnóstico de insulinorresistencia en la población española

Erardo Meriño-Ibarra, Ana Cenarro, Paula Martín, Ángel Luis García-Otín, Jesús Goicoechea, Ana Guallar, Luisa Calvo, Fernando Civeira

Journal:

Medicina Clínica

Year:

2007

File:

PDF, 74 KB

2007

37

Two novel missense mutations in LPL gene, G273V and R306H, in a subject with type I hyperlipoproteinemia

García-Otín, A.L., Fauré, E., Calvo, F., Ruiz, J.I., Recalde, D., Sanjurjo, P., Pocovi, M.

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000

38

MR. GLADSTONE ON MEDICAL EDUCATION.

García-Otín, A.L., Fauré, E., Calvo, F., Ruiz, J.I., Recalde, D., Sanjurjo, P., Pocovi, M.

Journal:

Year:

1876

Language:

english

File:

PDF, 178 KB

english, 1876

39

Th-P15:244 Carotid intima-media thickness differences between familial hypercholesterolemia and familial combined hyperlipidemia

Jarauta, E., Recalde, D., Cenarro, A., Martín-Fuentes, P., García-Otín, A.L., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 150 KB

english, 2006

40

Tu-P9:354 Correlation between carotid intima-media thickness and achilles tendon thickness in patients with heterozigous familial hypercholesterolemia

Jarauta, E., Cenarro, A., Martín-Fuentes, P., García-Otín, A.L., Recalde, D., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

41

GANGRENE OF AN EXTREMITY AS A COMPLICATION OF PNEUMONIA.

Jarauta, E., Cenarro, A., Martín-Fuentes, P., García-Otín, A.L., Recalde, D., Civeira, F.

Journal:

Year:

1922

Language:

english

File:

PDF, 204 KB

english, 1922

42

Chickadees get smarter as they move up mountains

Martin-Fuentes, P., Artieda, M., Recalde, D., Garcia-Otin, A.L., Jarauta, E., Cenarro, A., Civeira, F.

Journal:

Year:

2012

Language:

english

File:

PDF, 682 KB

english, 2012

43

HOSPITAL ABUSE.

Martin-Fuentes, P., Artieda, M., Recalde, D., Garcia-Otin, A.L., Jarauta, E., Cenarro, A., Civeira, F.

Journal:

Year:

1896

Language:

english

File:

PDF, 642 KB

english, 1896

44

Th-P15:247 Tendon xanthomas in familial hypercholesterolemia are associated with a pro-inflammatory cytokines profile in macrophages to oxidized LDL

Martin-Fuentes, P., Artieda, M., Recalde, D., Garcia-Otin, A.L., Jarauta, E., Cenarro, A., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

45

We-P11:275 Analysis of TLR-4 and CD14 polymorphisms in familial hypercholesterolaemia patients

Recalde, D., Martin-Fuentes, P., Puisac, B., Garcia-Otin, A.L., Cenarro, A., Jarauta, E., Lopez-Cabañas, J.A., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 302 KB

english, 2006

46

Análisis de las regiones reguladoras de la expresión de apo A-I en sujetos con hipoalfalipoproteinemia

Recalde, D., Cenarro, A., García-Otín, A.L., Tejedor, T., Civeira, F., Pocoví, M.

Journal:

Clínica e Investigación en Arteriosclerosis

Year:

2002

File:

PDF, 73 KB

2002

47

Th-P15:16 High intestinal cholesterol absorption associated with primary hypercholesterolemia non-related to defective LDL receptor

García-Otín, A.L., Cofán, M., Junyet, M., Recalde, D., Martín-Fuentes, P., Jarauta, E., Cenarro, A., Ros, E., Pocoví, M., Civeira, F.

Journal:

Atherosclerosis Supplements

Year:

2006

Language:

english

File:

PDF, 137 KB

english, 2006

48

Abstract: P838 SCREENING FOR PCSK9 MUTATIONS IN SPANISH PATIENTS WITH AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA UNRELATED TO LDLR OR APOB

García-Otín, á-L, Strunk, M, Pueyo, M, Solanas, M, Fiddyment, S, Aceves, M, Tejedor, D, Pocoví, M, Civeira, F

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 81 KB

english, 2009

49

Abstract: P927 FABP4 PLASMA LEVELS ARE ASSOCIATED WITH THE LIPID PROFILE OF FAMILIAL COMBINED HYPERLIPIDEMIA IN THE PRESENCE OF OBESITY

Cabre, A, Lazaro, I, Cofan, M, Jarauta, E, Plana, N, Garcia-Otin, A, Ascaso, J, Ferre, R, Civeira, F, Ros, E, Masana, L

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 85 KB

english, 2009

50

Abstract: P1293 PLASMA PHYTOSTEROLS AND METABOLIC SYNDROME. CROSSSECTIONAL STUDY IN DYSLIPIDEMIC PATIENTS AND HEALTHY SUBJECTS

Cofan, M, Escurriol, V, Garcia-Otin, A, Moreno-Iribas, C, Larrañaga, N, Tormo, M, Civeira, F, Ros, E

Journal:

Atherosclerosis Supplements

Year:

2009

Language:

english

File:

PDF, 86 KB

english, 2009

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